Category:BGT CHP NY ESO 1 Peptide Vaccine(B62771)
From BiomedGT
BGT_CHP-NY-ESO-1 Peptide Vaccine(B62771)
Lexical
Concept Code: B62771
(O)
Preferred Name: CHP-NY-ESO-1 Peptide Vaccine
Coding Scheme: BGT (09.06a )
Synonym: Cholesterol-Bearing Hydrophobized Pullulan NY-ESO-1 Protein (SY) (Source: NCI) / CHP-NY-ESO-1 Peptide Vaccine (PT) (Source: NCI)
Definition: A peptide vaccine containing nanoparticles of cholesterol-bearing hydrophobized pullulan (CHP) complexed with the cancer-testis antigen NY-ESO-1 protein with potential antineoplastic activity. NY-ESO-1, an antigen found in normal testis, is upregulated in various tumors, including bladder, breast, hepatocellular, melanoma, and prostate cancers. Vaccination with CHP-NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral as well as a cytotoxic T-cell response against tumor cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis. The self-aggregating CHP, composed of a pullulan backbone and cholesterol branches, forms stable colloidal nanoparticles in water. (Source: NCI)
URI: http://ncicb.nci.nih.gov/xml/owl/EVS/BiomedGT.owl#B62771
Properties
Semantic_Type: Pharmacologic Substance
Semantic_Type: Immunologic Factor
PDQ_Open_Trial_Search_ID: 489132
PDQ_Closed_Trial_Search_ID: 489132
Associations
Parent: Antineoplastic_Vaccine (primitive)
Form:LexWiki_BGT_Form
| BGT Concept Type(P365) | O + |
| BGT PDQ Closed Trial Search ID(P330) | 489132 +info.pngPDQ Closed Trial Search |
| BGT PDQ Open Trial Search ID(P329) | 489132 +info.pngPDQ Open Trial Search |
| BGT Semantic Type(P106) | Pharmacologic Substance +info.pngSemantic Type lookup , and Immunologic Factor +info.pngSemantic Type lookup |
| BGT Synonym(P104) | Cholesterol-Bearing Hydrophobized Pullulan NY-ESO-1 Protein +, and CHP-NY-ESO-1 Peptide Vaccine + |
| DCTerms hasVersion(hasVersion) | BGT/Versions/09.06a + |
| Has default form | LexWiki BGT Form + |
| LexWiki Concept Code | B62771 + |
| LexWiki Definition | A peptide vaccine containing nanoparticles … A peptide vaccine containing nanoparticles of cholesterol-bearing hydrophobized pullulan (CHP) complexed with the cancer-testis antigen NY-ESO-1 protein with potential antineoplastic activity. NY-ESO-1, an antigen found in normal testis, is upregulated in various tumors, including bladder, breast, hepatocellular, melanoma, and prostate cancers. Vaccination with CHP-NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral as well as a cytotoxic T-cell response against tumor cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis. The self-aggregating CHP, composed of a pullulan backbone and cholesterol branches, forms stable colloidal nanoparticles in water. (Source: NCI) idal nanoparticles in water. (Source: NCI) |
| LexWiki Preferred Name | CHP-NY-ESO-1 Peptide Vaccine + |
| LexWiki URI | http://ncicb.nci.nih.gov/xml/owl/EVS/BiomedGT.owl#B62771 + |
| SKOS inScheme(inScheme) | BGT + |
This category currently contains no articles or media.
