Category:CTCAE4 Endocrine disorders
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| Adverse Event | Grade1 | Grade2 | Grade3 | Grade4 | Grade5 |
|---|---|---|---|---|---|
| Adrenal insufficiency | Asymptomatic; clinical or diagnostic observations only; intervention not indicated | Moderate symptoms; medical intervention indicated | Severe symptoms; hospitalization indicated | Life-threatening consequences; urgent intervention indicated | Death |
| Cushingoid | Mild symptoms; intervention not indicated | Moderate symptoms; medical intervention indicated | Severe symptoms, medical intervention or hospitalization indicated | - | - |
| Delayed puberty | - | No breast development by age 13 yrs for females; testes volume of <3 cc or no Tanner Stage 2 development by age 14.5 yrs for males | No breast development by age 14 yrs for females; no increase in testes volume or no Tanner Stage 2 by age 16 yrs for males; hormone replacement indicated | - | - |
| Endocrine disorders - Other, specify | Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated | Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL | Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; disabling; limiting self care ADL | Life-threatening consequences; urgent intervention indicated | Death |
| Growth accelerated | - | >= +2 SD (standard deviation) above mid parental height or target height | - | - | - |
| Hyperparathyroidism | Mild symptoms; intervention not indicated | Moderate symptoms; medical intervention indicated | - | - | - |
| Hyperthyroidism | Asymptomatic; clinical or diagnostic observations only; intervention not indicated | Symptomatic; thyroid suppression therapy indicated; limiting instrumental ADL | Severe symptoms; limiting self care ADL; hospitalization indicated | Life-threatening consequences; urgent intervention indicated | Death |
| Hypoparathyroidism | Asymptomatic; clinical or diagnostic observations only; intervention not indicated | Moderate symptoms; medical intervention indicated | Severe symptoms; medical intervention or hospitalization indicated | Life-threatening consequences; urgent intervention indicated | Death |
| Hypothyroidism | Asymptomatic; clinical or diagnostic observations only; intervention not indicated | Symptomatic; thyroid replacement indicated; limiting instrumental ADL | Severe symptoms; limiting self care ADL; hospitalization indicated | Life-threatening consequences; urgent intervention indicated; | Death |
| Precocious puberty | Physical signs of puberty with no biochemical markers for females <8 years and males <9 years | Physical signs and biochemical markers of puberty for females <8 years and males <9 years | - | - | - |
| Virilization | Mild symptoms; intervention not indicated | Moderate symptoms; medical intervention indicated | - | - | - |
Articles in category "CTCAE4 Endocrine disorders"
There are 11 articles in this category.
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