Category:CTCAE4 Eye disorders
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| Adverse Event | Grade1 | Grade2 | Grade3 | Grade4 | Grade5 |
|---|---|---|---|---|---|
| Blurred vision | Intervention not indicated | Symptomatic; limiting instrumental ADL | Limiting self care ADL | - | - |
| Cataract | Asymptomatic; clinical or diagnostic observations only; intervention not indicated | Symptomatic; moderate decrease in visual acuity (20/40 or better) | Symptomatic with marked decrease in visual acuity (worse than 20/40 but better than 20/200); operative intervention indicated (e.g., cataract surgery) | Blindness (20/200 or worse) in the affected eye | - |
| Conjunctivitis | Asymptomatic or mild symptoms; intervention not indicated | Symptomatic; topical intervention indicated (e.g., antibiotics); limiting instrumental ADL | Limiting self care ADL | - | - |
| Corneal ulcer | - | Symptomatic; medical intervention indicated (e.g., topical agents); limiting instrumental ADL | Limiting self care ADL; declining vision (worse than 20/40 but better than 20/200) | Perforation or blindness (20/200 or worse) in the affected eye | - |
| Dry eye | Asymptomatic; clinical or diagnostic observations only; mild symptoms relieved by lubricants | Symptomatic; multiple agents indicated; limiting instrumental ADL | Decrease in visual acuity (<20/40); limiting self care ADL | - | - |
| Extraocular muscle paresis | Asymptomatic; clinical or diagnostic observations only | Symptomatic; limiting instrumental ADL | Limiting self care ADL; disabling | - | - |
| Eye disorders - Other, specify | Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated | Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL | Severe or medically significant but not immediately sight-threatening; hospitalization or prolongation of existing hospitalization indicated; disabling; limiting self care ADL | Sight-threatening consequences; urgent intervention indicated; blindness (20/200 or worse) in the affected eye | - |
| Eye pain | Mild pain | Moderate pain; limiting instrumental ADL | Severe pain; limiting self care ADL | - | - |
| Eyelid function disorder | Asymptomatic; clinical or diagnostic observations only; intervention not indicated | Symptomatic; nonoperative intervention indicated; limiting instrumental ADL | Limiting self care ADL; operative intervention indicated | - | - |
| Flashing lights | Symptomatic but not limiting ADL | Limiting instrumental ADL | Limiting self care ADL | - | - |
| Floaters | Symptomatic but not limiting ADL | Limiting instrumental ADL | Limiting self care ADL | - | - |
| Glaucoma | Elevated intraocular pressure (EIOP) with single topical agent for intervention; no visual field deficit | EIOP causing early visual field deficits; multiple topical or oral agents indicated; limiting instrumental ADL | EIOP causing marked visual field deficits (e.g., involving both superior and inferior visual fields); operative intervention indicated; limiting self care ADL | Blindness (20/200 or worse) in the affected eye | - |
| Keratitis | - | Symptomatic; medical intervention indicated (e.g., topical agents); limiting instrumental ADL | Decline in vision (worse than 20/40 but better than 20/200); limiting self care ADL | Perforation or blindness (20/200 or worse) in the affected eye | - |
| Night blindness | Symptomatic but not limiting ADL | Limiting instrumental ADL | Limiting self care ADL | Blindness (20/200 or worse) in the affected eye | - |
| Optic nerve disorder | Asymptomatic; clinical or diagnostic observations only | Limiting vision of the affected eye (20/40 or better); | Limiting vision in the affected eye (worse than 20/40 but better than 20/200) | Blindness (20/200 or worse) in the affected eye | - |
| Papilledema | Asymptomatic; no visual field defects | Symptomatic decline in vision; visual field defect present sparing the central 20 degrees | Marked visual field defect (worse than 20/40 but better than 20/200) | Blindness (20/200 or worse) in the affected eye | - |
| Photophobia | Symptomatic but not limiting ADL | Limiting instrumental ADL | Limiting self care ADL | - | - |
| Retinal detachment | Asymptomatic | Exudative and visual acuity 20/40 or better | Rhegmatogenous or exudative detachment; operative intervention indicated; decline in vision (worse than 20/40 but better than 20/200) | Blindness (20/200 or worse) in the affected eye | - |
| Retinal tear | - | Laser therapy or pneumopexy indicated | Vitroretinal surgical repair indicated | Blindness (20/200 or worse) in the affected eye | - |
| Retinal vascular disorder | - | Topical medication indicated | Intravitreal medication; operative intervention indicated | - | - |
| Retinopathy | Asymptomatic; clinical or diagnostic observations only | Symptomatic with moderate decrease in visual acuity (20/40 or better); limiting instrumental ADL | Symptomatic with marked decrease in visual acuity (worse than 20/40); disabling; limiting self care ADL | Blindness (20/200 or worse) in the affected eye | - |
| Scleral disorder | Asymptomatic; clinical or diagnostic observations only | Symptomatic, limiting instrumental ADL; moderate decrease in visual acuity (20/40 or better) | Symptomatic, limiting self care ADL; marked decrease in visual acuity (worse than 20/40) | Blindness (20/200 or worse) in the affected eye | - |
| Uveitis | Asymptomatic; clinical or diagnostic observations only | Anterior uveitis; medical intervention indicated | Posterior or pan-uveitis | Blindness (20/200 or worse) in the affected eye | - |
| Vitreous hemorrhage | Asymptomatic or mild symptoms; clinical or diagnostic observations only | Symptomatic; limiting instrumental ADL | Limiting self care ADL; vitrectomy indicated | Blindness (20/200 or worse) in the affected eye | - |
| Watering eyes | Intervention not indicated | Intervention indicated | Operative intervention indicated | - | - |
Articles in category "CTCAE4 Eye disorders"
There are 25 articles in this category.

